PE-Labeled Human CD27 Ligand / CD70 Protein, His TagStar Staining

DESCRIPTION

Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.

DETAILS

Tag: N-10×His
Host: HEK293
Size: 200tests
Buffer: PBS, 0.2% BSA, pH7.4
Format: Powder
Purity: 90%
Source: PE-Labeled Human CD27 Ligand Protein, His Tag (CDL-HP246) is produced via conjugation of PE to Human CD27 Ligand Protein, His Tag with a new generation site-specific technology under Star Staining labeling platform. Human CD27 Ligand Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 52 - Pro 193 (Accession # P32970-1).
Storage: -20℃, aviod light
Category: Fluorescent labeled protein
Molecule: CD27 Ligand
Conjugate: PE Labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ser 52 - Pro 193
Swiss-prot: P32970-1
Package Size: 200tests*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 61.6 kDa.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 61.6 kDa
Shipping Condition: RT
Species Reactivity: Human
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