4821-MSM1-P0 4821-MSM1-P1 4821-MSM1-P1ABX
NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) - CloneID - NX2/294
NeoBiotechnologies
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DESCRIPTION
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
DETAILS
- Host: Mouse
- Gene ID: 4821
- Uniprot: O95096
- Clone ID: NX2/294
- Clonality: Monoclonal
- Gene Name: NKX2-2
- Supplied As: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Applications: FLOW, IHC, IF
- Protein Target: NKX2-2
- Species Reactivity: Human, Mouse, Rat, Chicken
- Storage Conditions: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.