TMPY-06986
FGF-8b Protein, Human, Recombinant
TargetMol
DESCRIPTION
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.
DETAILS
- Purity: 98%
- Category: Compound
- Molecular Weight: The recombinant human FGF8b consists 194 amino acids and predicts a molecular mass of 22.5 kDa.
Lead Time: < 1 week
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