DESCRIPTION

• Form: Protein G Purified
• Gene: SNCA
• Host: Mouse
• Rrid: AB_2889896
• Type: Primary Antibody
• Clone: 2A7
• Buffer: PBS + 50% glycerol and 5 mm NaN3
• Target: Alpha Synuclein
• Isotype: IgG1
• Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
• Shipping: Blue Ice
• Synonyms: Alpha synuclein antibody, Alpha-synuclein antibody, Alpha-synuclein, isoform NACP140 antibody, alphaSYN antibody, MGC105443 antibody, MGC110988 antibody, MGC127560 antibody, MGC64356 antibody, NACP antibody, Non A beta component of AD amyloid antibody, Non A4 component of amyloid antibody, Non A4 component of amyloid precursor antibody, Non-A beta component of AD amyloid antibody, Non-A-beta component of alzheimers disease amyloid , precursor of antibody, Non-A4 component of amyloid precursor antibody, Non-A4 component of amyloid, precursor of antibody, OTTHUMP00000218549 antibody, OTTHUMP00000218551 antibody, OTTHUMP00000218552 antibody, OTTHUMP00000218553 antibody, OTTHUMP00000218554 antibody, PARK 1 antibody, PARK 4 antibody, PARK1 antibody, PARK4 antibody, Parkinson disease (autosomal dominant Lewy body) 4 antibody, Parkinson disease familial 1 antibody, SNCA antibody, Snca synuclein alpha (non A4 component of amyloid precursor) antibody, SYN antibody, Synuclein alpha antibody, Synuclein alpha 140 antibody, Synuclein alpha (non A4 component of amyloid precursor) antibody, SYUA_HUMAN antibody
• Clonality: Monoclonal
• Immunogen: Full length human alpha synuclein expressed in E. Coli.
• Expiration: After date of receipt, stable for at least 1 year at -20°C.
• Specificity: Specific for the endogenous levels of the ~15 kDa alpha synuclein protein.
• Applications: WB, IHC, ICC
• Ncbi Gene Id: 6622
• Conjugate Exem: Unconjugated
• Physical State: Liquid
• Quality Control: Western blots performed on each lot.
• Usage Statement: For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
• Molecular Weight: 15
• Production Notes: Protein G purified.
• Dilution Range Wb: 1:1000
• Immunogen Species: Human
• Dilution Range Icc: 1:1000
• Dilution Range Ihc: 1:1000
• Species Reactivity: Bovine, Human, Mouse, Pig, and Rat
• Target Description: Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson’s disease (PD) and other neurodegenerative disorders (Okochi et al., 2000). Early onset Parkinson's disease may be caused by a duplication or triplication of one of the alpha synuclein genes (ChartierHarlin MC et al., 2004 and Singleton, AB et al., 2005). Alpha-synuclein is also found in the Lewy bodies of patients with diffuse Lewy body disease and inclusions in glial cells in the brains of patients with multiple system atrophy (MSA) and amyotrophic lateral sclerosis (ALS).
• Dilution Range Wb Brain: 1:1000
• Uniprot Number Immunogen Species: P37840

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