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Human Raftlin, RFTN1 ELISA Kit

Bioassay Technology Laboratory


Involved in protein trafficking via association with clathrin and AP2 complex (PubMed: 27022195, PubMed: 21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed: 27022195, PubMed: 21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed: 12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed: 12805216).


  • GeneID: 23180
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 63,146
  • Synonyms: Cell migration-inducing gene 2 protein;Raftlin;Raft-linking protein;RFTN 1;RFTN1
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: RFTN1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.41ng/ml
  • Target Protein: RFTN1
  • Detection Range: 0.5-40ng/ml
  • Full Product Name: Raftlin
  • Standard Solution: 48ng/ml
  • UniProt Accession: Q14699