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NC4-C82F7-25ug NC4-C82F7-200ug

Biotinylated Cynomolgus NKG2A&CD94 Protein, Fc,Avitag™ (MALS verified)

ACROBiosystems

DESCRIPTION

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

DETAILS

  • Tag: C-Fc & C-Avi
  • Host: HEK293
  • Size: 200ug
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 95%
  • Source: Biotinylated Cynomolgus NKG2A&CD94, Fc,Avitag (NC4-C82F7) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # Q68VD2 (NKG2A) & Q68VD4 (CD94)).
  • Storage: -20℃
  • Category: MABSol® Biotin Labeled Proteins
  • Molecule: NKG2A & CD94
  • Conjugate: Biotin-labeled
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Exp Region: Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)
  • Swiss-prot: Q68VD2 (NKG2A) & Q68VD4 (CD94)
  • Package Size: 200ug*1
  • Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 56.8 kDa. The protein migrates as 65-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 56.8 kDa
  • Shipping Condition: RT
  • Species Reactivity: Cynomolgus
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html