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TMS1461

Qingyangshengenin B

TargetMol

- Open Babel Depiction O O O H 3 C H 3 C O CH 3 HO O O CH 3 OH CH 3 O CH 3 O O O H 3 C OH CH 3 O O H 3 C H 3 C CH 3 H 3 C OH

DESCRIPTION

Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Qingyangshengenin B has antiepileptic and anti-aging effects, it can extend lifespan, increase heat stress-resistance, delay body paralysis, and increase the chemotaxis response in C. elegans models of Alzheimer's disease. Otophylloside B can suppress the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.

DETAILS

  • Cas: 106758-54-7
  • Purity: 99.26%
  • Smiles: O[C@]12[C@](C)([C@H](OC(/C=C(/C(C)C)\C)=O)C[C@]3([C@@]1(O)CC=C4[C@]3(C)CC[C@H](O[C@H]5C[C@H](OC)[C@H](O[C@H]6C[C@H](OC)[C@H](O[C@H]7C[C@@H](OC)[C@H](O)[C@@H](C)O7)[C@@H](C)O6)[C@@H](C)O5)C4)[H])[C@@](C(C)=O)(O)CC2
  • Category: Compound
  • Molecular Weight: 923.13
  • Molecular Formula: C49H78O16

Lead Time: 4 - 5 weeks

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