RP00166
Recombinant Human TNFRSF12A/TWEAKR/CD266 Protein
ABclonal
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DESCRIPTION
Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Human and mouse TNFRSF12A share 82% aa sequence identity. TNFRSF12A transcript was expressed at high levels in heart, placenta, and kidney, at intermediate levels in lung, skeletal muscle, and pancreas, and at low levels in brain and liver. In addition, elevated TNFRSF12A expression was found in human liver cancer cell lines and hepatocellular carcinoma specimens. TNFRSF12A is the weak inducer of apoptosis in some cell types. It promotes angiogenesis and the proliferation of endothelial cells. TNFRSF12A may modulate cellular adhesion to matrix proteins.
DETAILS
- Tag: C-hFc&His
- Source: HEK293 cells
- Gene Id: 51330
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: Q9NP84
- Research Areas: Bio-Markers & CD Antigens,TNF family,Biosimilar Drug Targets
- Alternative Names: CD266, FN14, TWEAKR,TNFRSF12A,FN14,TWEAKR
Equivalent Items
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