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E1006Hu

Human Erythropoietin Receptor, EPOR ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

DETAILS

  • GeneID: 2057
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 55,065
  • Synonyms: EPOR;EPO-R;Erythropoietin receptor
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: EPOR
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 9.04ng/L
  • Target Protein: EPOR
  • Detection Range: 20-6000ng/L
  • Full Product Name: Erythropoietin Receptor
  • Standard Solution: 6400ng/L
  • UniProt Accession: P19235