Skip to Main Content
Welcome to the Marketplace

Go to Main Navigation


Recombinant Human MDC (CCL22) (67 a.a.)



MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells, and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells, and exerts HIV-suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity, but retains HIV-suppressive activity. Recombinant Human MDC is an 8.0 kDa protein containing 67 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.


  • Gene Id: 6367
  • Uniprot: O00626
  • Activity: Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml.
  • Category: RUO Cytokines
  • Subcategory: Chemokines
  • Research Areas: AIDS/HIV, Chemotaxis, Immune System, Wound Healing
  • Alternative Names: Macrophage-Derived Chemokine, CCL22, STCP-1, ABCD-1
  • Species of Origin: Human
  • Expression System Source: E.coli