TMPK-00875
CD96 Protein, Human, Recombinant (His & Avi), Biotinylated
TargetMol
DESCRIPTION
The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.
DETAILS
- Cas: TMPK-00875
- Purity: 98%
- Category: Compound
- Molecular Weight: The protein has a predicted MW of 59.1 kDa. Due to glycosylation, the protein migrates to 115-140 kDa based on Tris-Bis PAGE result.
Lead Time: 4 - 5 weeks
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