B0084-007837
SAR-20347
BOC Sciences
DETAILS
- Iupac: 2-(2-chloro-6-fluorophenyl)-5-[4-(morpholine-4-carbonyl)anilino]-1,3-oxazole-4-carboxamide
- Smiles: C1COCCN1C(=O)C2=CC=C(C=C2)NC3=C(N=C(O3)C4=C(C=CC=C4Cl)F)C(=O)N
- Aliases: 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide; SAR 20347; SAR20347
- Cas Number: 1450881-55-6
- Molecular Weight: 444.84
- Molecular Formula: C21H18ClFN4O4
DESCRIPTION
SAR-20347 is a dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2) with IC50 values of 23 and 0.6 nM, respectively. It also exhibits slight inhibitory effects gainst JAK2 and JAK3.