T78803
SIRT5 inhibitor 7
TargetMol
DESCRIPTION
SIRT5 inhibitor 7 (compound 58), a selective and substrate-competitive SIRT5 inhibitor, exhibits anti-inflammatory properties by modulating protein succinylation and attenuating pro-inflammatory cytokine release. It demonstrates renal protective effects and is active in vivo, showing efficacy in AKI mouse models subjected to lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury [1].
DETAILS
- Cas: 2951090-00-7
- Purity: 98%
- Category: Compound
- Molecular Weight: 582.12
- Molecular Formula: C28H32ClN7O3S
Lead Time: 4 - 5 weeks
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