DESCRIPTION

• Mw: 14.9 kDa
• Tag: Myc-DDK
• Accn: NM_018476
• Type: Human Tagged ORF Clone Lentiviral Particle
• Refseq: NM_018476.3
• Status: 5 Weeks*
• Symbol: BEX1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Domains: BEX
• Category: cDNA Clones
• Locus Id: 55859
• Orf Size: 375 bp
• Synonyms: BEX2; HBEX2; HGR74-h
• Refseq Orf: 378 bp
• Uniprot Id: Q9HBH7
• Refseq Size: 862 bp
• Availability: 5 Weeks
• Cytogenetics: Xq22
• Gene Summary: Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).[UniProtKB/Swiss-Prot Function]
• Sequence Data: ORF Nucleotide Sequence ( show hide ) The ORF insert of this clone is exactly the same as(RC220965).
• Oti Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Oti Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Mammalian Cell Selection: Puromycin