FCM-R82W7-25ug FCM-R82W7-200ug
Biotinylated Rat FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Strep II Tag (MALS & SPR verified)
ACROBiosystems
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DESCRIPTION
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
DETAILS
- Tag: C-Avi & C-10×His | C-Strep II
- Host: HEK293
- Size: 25ug
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 95%
- Source: MABSol® Biotinylated Rat FCGRT&B2M Heterodimer Protein, Avitag,His Tag&Strep II Tag (FCM-R82W7) is expressed from human HEK293 cells. It contains AA Ala 23 - Ser 298 (FCGRT) & Ile 21 - Met 119 (B2M) (Accession # P13599-1 (FCGRT) & P07151-1 (B2M)).
- Storage: -20℃
- Category: MABSol® Biotin Labeled Proteins
- Molecule: FcRn (FCGRT & B2M)
- Accession: NP_203502.1 (FCGRT) & NP_036644.1 (B2M)
- Conjugate: Biotin-labeled
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Ala 23 - Ser 298 (FCGRT) & Ile 21 - Met 119 (B2M)
- Swiss-prot: P13599-1 (FCGRT) & P07151-1 (B2M)
- Package Size: 25ug*1
- Characteristics: Biotinylated Rat FCGRT&B2M Heterodimer Protein, Avitag,His Tag&Strep II Tag, produced by co-expression of FCGRT and B2M, has a calculated MW of 34.7 kDa (FCGRT) and 13.1 kDa (B2M). Subunit FCGRT is fused with an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag and subunit Beta-2 microglobulin (B2M) is fused with a Strep II tag at the C-terminus. The reducing (R) protein migrates as 45-50 kDa (FCGRT) and 14 kDa (B2M) respectively due to different glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 34.7 kDa (FCGRT), 13.1 kDa (B2M)
- Shipping Condition: RT
- Species Reactivity: Rat
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html