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HY-131902

MLT-231

MedChem Express

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DETAILS

  • Purity: >98%
  • Smiles: O=C(NC1=C(N2[C@@H](C)COC[C@@H]2C)N3C(N=C1)=CC(Cl)=N3)NC4=CC=NC(C(F)(F)F)=C4
  • Category: Reference compound
  • Lead Time: 1-2 days
  • Cas Number: 2682102-10-7
  • Molecular Weight: 469.85
  • Molecular Formula: C19H19ClF3N7O2

DESCRIPTION

MLT-231 is a potent, highly selective allosteric MALT1 Inhibitor with an IC50 of 9 nM. MLT-231 specifically prevents endogenous BCL10 cleavage with IC50 of 160 nM. MLT-231 shows antitumor activity in an ABC-DLBCL type xenograft model in mouse[1].

Lead Time: 1-2 days

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