mouse monoclonal IgG1; ANP Antibody (F-2) is an IgG1 κ mouse monoclonal ANP antibody (also designated natriuretic peptide precursor A (NPPA) antibody, natriuretic peptide A antibody, electrolyte homeostasis related antibody, extracellular fluid (ECF) volume sodium excretion related antibody, Atrial Natriuretic Factor (ANF) antibody, atrial cardiac muscle cell secreted protein antibody, cardiac hormone/paracrine related antibody, familial atrial fibrillation-6 (ATFB6) antibody, or Atrial Dilation and Standstill (ATRST2) antibody) that detects the ANP protein of mouse, rat and human origin by WB, IP, IF and ELISA. ANP Antibody (F-2) is available as both the non-conjugated anti-ANP antibody form, as well as multiple conjugated forms of anti-ANP antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage. The genes which encode for ANP and BNP map to human chromosome 1p36.2. The gene which encodes for CNP maps to human chromosome 2q24-qter.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.