ABCE1 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 6059
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: ABCE1
Other Names: ATP-binding cassette sub-family E member 1, 2'-5'-oligoadenylate-binding protein, HuHP68, RNase L inhibitor, Ribonuclease 4 inhibitor, RNS4I, ABCE1, RLI, RNASEL1, RNASELI, RNS4I
Availability: 2 weeks
Bio Background: The protein encoded by this gene is a member of thesuperfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- andintra-cellular membranes. ABC genes are divided into seven distinctsubfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Thisprotein is a member of the OABP subfamily. Alternatively referredto as the RNase L inhibitor, this protein functions to block theactivity of ribonuclease L. Activation of ribonuclease L leads toinhibition of protein synthesis in the 2-5A/RNase L system, thecentral pathway for viral interferon action. Two transcriptvariants encoding the same protein have been found for this gene.
Bio References: Huang, B., et al. Int. J. Mol. Med. 25(5):687-693(2010)Pisarev, A.V., et al. Mol. Cell 37(2):196-210(2010)Crawford, D.C., et al. Genes Immun. 10(8):715-721(2009)Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)Shea, P.R., et al. Prostate 68(4):354-359(2008)
Primary Accession: P61221