Human FKBP4 / FKBP52 Protein, His,PA Tag

DESCRIPTION

Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52. FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.

DETAILS

Tag: C-10×His & C-PA Tag
Host: HEK293
Size: 500ug
Buffer: 50 mM Tris, 100 mM Glycine, pH7.5
Format: Powder
Purity: 95%
Source: Human FKBP4, His,PA Tag (FK4-H52Q3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 459 (Accession # AAH01786).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: FKBP4
Accession: AAH01786
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Met 1 - Ala 459
Swiss-prot: Q02790
Package Size: 100ug*5
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by a PA tag, and has a calculated MW of 55.1 kDa. The reducing (R) protein migrates as 60 kDa in SDS-PAGE.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 55.1 kDa
Shipping Condition: RT
Species Reactivity: Human
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