PPIase Recombinant Protein

DESCRIPTION

Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ,skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

DETAILS

Buffer: Supplied as a 0.2 um filtered solution of 20mM TrisHCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Purity: Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Source: E. coli
Species: Human
Storage: Store at -20˚C, stable for 6 months after receipt.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: Dry Ice
By Source: E. Coli
Swissprot: Q9Y3C6
By Species: Human
Fusion Tag: N-6 His tag
Ncbi Gene Id: 51645
Ncbi Organism: Homo sapiens
Physical State: Liquid
Additional Names: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1, PPIase, Rotamase PPIL1, PPIL1, CYPL1
Application Note: This recombinant protein can be used for biological assays. For research use only.
By Research Area: Immunology,Signal Transduction
Protein Accession: Q9Y3C6
Ncbi Official Name: peptidylprolyl isomerase like 1
Ncbi Official Symbol: PPIL1
Predicted Molecular Weight: 20.4 kD
Recombinant Protein Sequence: Met1-Gly166