1975-STGt 1975-STG
Promo Available
Anti-Synaptotagmin 1 Antibody
PhosphoSolutions
DESCRIPTION
Our Anti-synaptotagmin 1 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat synaptotagmin 1 and is antigen affinity purified from pooled serum. It is great for use in WB.
DETAILS
- Form: Antigen Affinity Purified from Pooled Serum
- Gene: SYT1
- Host: Rabbit
- Rrid: AB_2492251
- Type: Primary Antibody
- Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
- Target: Synaptotagmin 1
- Isotype: IgG
- Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
- Shipping: Blue Ice
- Synonyms: DKFZp781D2042 antibody, FLJ42519 antibody, P65 antibody, SVP65 antibody, synaptotagmin 1 antibody, Synaptotagmin I antibody, SYT antibody, SYT1 antibody, SytI antibody
- Clonality: Polyclonal
- Immunogen: Synthetic peptide corresponding to amino acid residues specific to rat synaptotagmin 1, conjugated to keyhole limpet hemocyanin (KLH).
- Expiration: After date of receipt, stable for at least 1 year at -20°C.
- Specificity: Specific for endogenous levels of the ~65 kDa synaptotagmin I protein.
- Applications: WB
- Ncbi Gene Id: 25716
- Conjugate Exem: Unconjugated
- Physical State: Liquid
- Quality Control: Western blots performed on each lot.
- Usage Statement: For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
- Molecular Weight: 65
- Production Notes: Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
- Dilution Range Wb: 1:1000
- Immunogen Species: Rat
- Species Reactivity: Mouse and Rat
- Target Description: Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006).
- Expected Reactivity: Bovine, Chicken, Human, Non-Human Primate
- Dilution Range Wb Brain: 1:1000
- Uniprot Number Immunogen Species: P21707
PROMOTION TERMS
Trial Size Available. Limit 1
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