HCoV-229E Nucleocapsid protein, His Tag

DESCRIPTION

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

DETAILS

Tag: N-6×His
Host: E. coli
Size: 1mg
Buffer: 40 mM PB, 500 mM NaCl, pH7.4
Format: Powder
Purity: 90%
Source: HCoV-229E Nucleocapsid, His Tag (NUN-V5147) is expressed from E. coli cells. It contains AA Met 1 - Asn 389 (Accession # P15130-1).
Storage: -20℃
Category: Viral Proteins
Molecule: Nucleocapsid protein
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Met 1 - Asn 389
Swiss-prot: P15130-1
Package Size: 250ug*4
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 44.4 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 44.4 kDa
Shipping Condition: RT
Species Reactivity: HCoV-229E
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