E6880Hu
Human Mitochondrial-derived Peptide Mots-C, MT-RNR1 ELISA Kit
Bioassay Technology Laboratory
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DESCRIPTION
Regulates insulin sensitivity and metabolic homeostasis. Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5'-AMP-activated protein kinase (AMPK). Protects against age-dependent and diet-induced insulin resistance as well as diet-induced obesity.
DETAILS
- GeneID: 4549
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 2,175
- Synonyms: Mitochondrial open reading frame of the 12S rRNA-c;Mitochondrial-derived Peptide MOTS-c;MTRNR1;MT-RNR1;RNR1
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: MT-RNR1
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 4.08ng/L
- Target Protein: MT-RNR1
- Detection Range: 7-1500ng/L
- Full Product Name: Mitochondrial-derived Peptide MOTS-c
- Standard Solution: 1600ng/L
- UniProt Accession: A0A0C5B5G6