Features a soft, extra thick, conformable adhesive ThermalSeal 2 and ThermalSeal Advanced feature a soft, extra thick, conformable adhesive that forms a very strong seal around raised wells to minimize evaporation and cross-contamination. Certified DNase- & RNase- free Ideal for use with flat-top, semi-skirted and full-skirted PCR plates Compatible with hard-shell dual component (e.g. polycarbonate/polypropylene) PCR plates Large cut allows for easier positioning of the film to the plate via edge of plate alignment vs. centering Available in a smaller cut for raised-rim and non-skirted PCR plates: ThermalSeal Advanced Helpful Tips: Selection of the proper film size will minimize evaporation The film should not overhang or ride up the wall of a raised-rim plate More complete coverage of skirted flat-top plates will reduce evaporation in the outer wells End-tab removal before thermal cycling is highly recommended