sc-59348
Scientist.com Supplier
PSG1 (BAP3)
Santa Cruz Biotechnology
Image
DESCRIPTION:
mouse monoclonal IgG1; PSG1 Antibody (BAP3) is an IgG1 κ mouse monoclonal PSG1 antibody (also designated PSG1 antibody) that detects the PSG1 protein of human origin by WB, IP, IF and FCM. PSG1 Antibody (BAP3) is available as both the non-conjugated anti-PSG1 antibody form, as well as multiple conjugated forms of anti-PSG1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Pregnancy specific glycoprotein 1 (PSG1), also designated CD66f, is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. Eleven human PSG proteins (PSG1-PSG11) have been described.
DETAILS
- Host: mouse
- Uniprot: P11464
- Clonality: Monoclonal
- Conjugate: unconjugated
- Applications: WB, IP, IF, FCM
- Human Gene Id: 5669
- Protein Target: PSG1
- Human Gene Name: PSG1
- Species Reactivity: human
Equivalent Items
| ... Loading