PLV-H82E3-25ug PLV-H82E3-100ug PLV-H82E3-200ug
Biotinylated Human Platelet glycoprotein V Protein, His,Avitag™ (MALS verified)
ACROBiosystems
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DESCRIPTION
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]
DETAILS
- Tag: C-10×His & C-Avi
- Host: HEK293
- Size: 100ug
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 95%
- Source: Biotinylated Human Platelet glycoprotein V Protein, His,Avitag (PLV-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gln 17- Gly 523 (Accession # P40197).
- Storage: -20℃
- Category: MABSol® Biotin Labeled Proteins
- Molecule: Platelet glycoprotein V
- Conjugate: Biotin-labeled
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Gln 17- Gly 523
- Swiss-prot: P40197
- Package Size: 100ug*1
- Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 58.6 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 58.6 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html