BP8804c
SCNN1A Antibody (Center) Blocking Peptide
Abcepta
DETAILS
- Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
- Gene Id: 6337
- Category: Peptides; Blocking Peptides
- Subtitle: Synthetic peptide
- Gene Name: SCNN1A
- Other Names: Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Alpha-ENaC, ENaCA, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA, SCNN1A, SCNN1
- Availability: 2 weeks
- Bio Background: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been sociated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids.
- Bio References: Azad A.K., et.al., Hum. Mutat. 30:1093-1103(2009).
- Primary Accession: P37088
- Targetspecificity: The synthetic peptide sequence used to generate the antibody AP8804c was selected from the Center region of human SCNN1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.