E1566Hu
Human Semaphorin 4D, SEMA4D ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed: 20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed: 19788569). Promotes the migration of cerebellar granule cells (PubMed: 16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed: 8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PubMed: 16055703).
DETAILS
- GeneID: 10507
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 96,150
- Synonyms: A8;BB18;CD antigen CD100;GR3;SEMA4D;Semaphorin-4D
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: SEMA4D
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 0.1ng/ml
- Target Protein: SEMA4D
- Detection Range: 0.2-60ng/ml
- Full Product Name: Semaphorin 4D
- Standard Solution: 64ng/ml
- UniProt Accession: Q92854