Human PVRIG Protein, Mouse IgG2a Fc Tag (MALS verified)

DESCRIPTION

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

DETAILS

Tag: C-mFc(mIgG2a)
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Human PVRIG, Mouse IgG2a Fc Tag (PVG-H5259) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # Q6DKI7-1).
Storage: -20℃
Category: Immune Checkpoint Proteins
Molecule: PVRIG
Accession: NP_076975.2
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Thr 41 - Asp 171
Swiss-prot: Q6DKI7-1
Package Size: 500ug*2
Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 40.7 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 40.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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