DESCRIPTION

• Tag: C-6×His Tag
• Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
• Source: Mammalian
• Species: Human
• Uniprot: P04275
• Activity: Yes
• Category: Proteins
• Conjugate: Unconjugated
• Gene Name: VWF
• Lead Time: In Stock
• Background: This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
• Alias Names: F8VWF;VWD
• Subcategory: Recombinant ECD Proteins
• Product Type: Recombinant ECD Proteins
• Protein Name: VWF
• Purification: Purified from cell culture supernatant by affinity chromatography
• Molecular Weight: The protein has a predicted molecular mass of 82.2 kDa after removal of the signal peptide. The apparent molecular mass of VWF(23-763)-His is approximately 100-130 kDa due to glycosylation.
• Storage Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
• Molecular Characterization: VWF(Ala23-Arg763) 6×His tag
• Formulation Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

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