RP00044
Recombinant Human MANF Protein
ABclonal
DESCRIPTION
The protein is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing this protein increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
DETAILS
- Tag: C-His
- Source: E. coli
- Gene Id: 7873
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: P55145
- Research Areas: Growth Factor
- Alternative Names: MANF,ARMET,ARP
Equivalent Items
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