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sc-390977 SAMPLE sc-390977

Promo Available Scientist.com Supplier

ACTR-II (F-12)

Santa Cruz Biotechnology

DESCRIPTION

mouse monoclonal IgG2a; ACTR-II Antibody (F-12) is an IgG2a κ mouse monoclonal ACTR-II antibody (also designated AVR2A antibody, AVR2B antibody, Activin A Receptor Type 2B antibody, Activin A Receptor Type 2A antibody, Activin A Receptor Type IIB antibody, Activin Receptor Type-2BA antibody, ActR-IIB antibody, Activin Receptor Type IIA antibody, ACTR-IIB antibody, ACTRIIB antibody, ACVR2B antibody, or HTX4 antibody) that detects the ACTR-II protein of human origin by WB, IP, IF, IHC(P) and ELISA. ACTR-II Antibody (F-12) is available as both the non-conjugated anti-ACTR-II antibody form, as well as multiple conjugated forms of anti-ACTR-II antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion.

DETAILS

  • Host: mouse
  • Type: Primary
  • Uniprot: Q13705
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, IHC(P), ELISA
  • Human Gene Id: 92 93
  • Protein Target: ACTR-IIA and ACTR-IIB
  • Human Gene Name: ACVR2A, ACVR2B
  • Species Reactivity: human

PROMOTION TERMS

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.