16214
Benztropine (mesylate)
Cayman Chemical
DESCRIPTION
An M1 muscarinic acetylcholine receptor antagonist (Ki = 0.59 nM in rat brain membranes); selective for M1 receptors over the serotonin transporter (Ki = 5,150 nM); binds to the dopamine transporter and inhibits dopamine reuptake (Kis = 237 and 130 nM, respectively); inhibits acid sphingomyelinase by 87% at 10 mM
DETAILS
- Inchi: InChI=1S/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-5(2,3)4/h2-11,18-21H,12-15H2,1H3;1H3,(H,2,3,4)/t18-,19+,20+;
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease
- Smiles: CN1[C@@H]2C[C@@H](OC(C3=CC=CC=C3)C4=CC=CC=C4)C[C@H]1CC2.OS(C)(=O)=O
- Inchikey: CPFJLLXFNPCTDW-BWSPSPBFSA-N
- Cas Number: 132-17-2
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C21H25NO • CH3SO3H
- Formula Weight: 403.5
- Shelf Life Days: 1460