Human Podoplanin / PDPN Protein, His Tag (SPR verified)

DESCRIPTION

Podoplanin (PDPN) is a type I transmembrane mucin-like glycoprotein expressed in the lymphatic endothelium. It is overexpressed in several solid tumors, such as squamous cell carcinoma, malignant mesothelioma, Kaposi sarcoma, angiosarcoma, testicular seminoma, and brain tumors. PDPN expression is associated with malignant progression, epithelial–mesenchymal transition, and metastasis.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Human Podoplanin, His Tag (PON-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Leu 131 (Accession # Q86YL7-1).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: Podoplanin
Accession: NP_006465.3
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 23 - Leu 131
Swiss-prot: Q86YL7-1
Package Size: 500ug*2
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 13.0 kDa. The protein migrates as 19-21 kDa and 30-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 13.0 kDa
Shipping Condition: RT
Species Reactivity: Human
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