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AF-100-19

Animal-Free Recombinant Human KGF (FGF-7)

PeproTech

DETAILS

  • Gene Id: 2252
  • Uniprot: P21781
  • Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml.
  • Category: RUO Cytokines
  • Subcategory: Animal-Free Cytokines
  • Research Areas: Angiogenesis/Cardiovascular, FGF Superfamily, Immune System, Stem Cells and Differentiation, Wound Healing, Diabetes/Weight Regulation
  • Alternative Names: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
  • Species of Origin: Human
  • Expression System Source: E.coli

DESCRIPTION

KGF (FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF-7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF (FGF-7) signals through FGFR 2b. KGF (FGF-7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Human KGF (FGF-7) is an 18.9 kDa protein consisting of 163 amino acid residues.