DESCRIPTION

• Target: NOS1
• Gene Id:  4842
• Isotype: IgG2a
• Conjugate: HRP
• Immunogen: Partial Human Recombinant NOS1 Protein
• Swiss-prot: P29475
• Specificity: Detects ~160.97 kDa.
• Applications: WB | ICC/IF | ELISA | IHC
• Clone Number: J23
• Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• Host Species: Mouse
• Product Type: Monoclonal
• Purification: Protein A Purified
• Concentration: 1mg/ml
• Research Areas: Neuroscience | Neurotransmission | Nitric Oxide | Cancer | Cancer Metabolism | Response to Hypoxia
• Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium azide *Storage buffer may change when conjugated
• Accession Number: NP_000611.1
• Alternative Names: BNOS Antibody, Constitutive NOS Antibody, IHPS 1 Antibody, IHPS1 Antibody, N-NOS Antibody, NC-NOS Antibody, neuronal Nitric Oxide Synthase Antibody, Neuronal NOS Antibody, Nitric oxide synthase neuronal included Antibody, Nitric oxide synthase 1 (neuronal) Antibody, Nitric oxide synthase 1 Antibody, NNOS Antibody, NO Antibody, NOS 1 Antibody, NOS Antibody, NOS type I Antibody, NOS-I Antibody, NOS1 Antibody, NOS1_HUMAN Antibody
• Antibody Dilution: WB (1:1000); optimal dilutions for assays should be determined by the user.
• Cite This Product: Mouse Anti-Human NOS1 Monoclonal (StressMarq Biosciences, Victoria BC, Cat# SMC-609D-HRP)
• Immunogen Species: Human
• Tissue Specificity: Ubiquitously expressed; detected in skeletal muscle and brain, also in testis, lung and kidney.
• Storage Temperature: Conjugated antibodies should be stored according to the product label
• Shipping Temperature: Blue Ice or 4ºC
• Cellular Localization: Cell Membrane
• Scientific Background: nNOS/NOS I, also known as NC-NOS, or NOS type I, or Neuronal NOS, or produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Nitric oxide production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. There are two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II).
• Certificate of Analysis: A 1:1000 dilution of SMC-609 was sufficient for detection of NOS1/Nnos in 7.5 ug of Mouse Brain Cerebellum by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
• Species Reactivity Full Name: Human | Mouse | Rat