Mouse Pak2 Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 224105
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: Pak2
Other Names: Serine/threonine-protein kinase PAK 2, Gamma-PAK, p21-activated kinase 2, PAK-2, PAK-2p27, PAK-2p34, Pak2
Availability: 2 weeks
Bio Background: The activated kinase acts on a variety of targets. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD. Caspase-activated PAK-2p34 is involved in cell death response, probably involving the JNK signaling pathway (By similarity).
Bio References: Jiang, X.S., et al. Hum. Mol. Genet. 19(7):1347-1357(2010)Demyanenko, G.P., et al. Neuroscience 165(1):107-115(2010)Grimsley-Myers, C.M., et al. J. Neurosci. 29(50):15859-15869(2009)Hsuuw, Y.D., et al. Ann. N. Y. Acad. Sci. 1171, 501-508 (2009) :Van den Broeke, C., et al. Proc. Natl. Acad. Sci. U.S.A. 106(21):8707-8712(2009)
Primary Accession: Q8CIN4