IL34 Human

DESCRIPTION

Source:CHO cells.Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.Biological ActivitynullInterleukin 34 (IL34) is a cytokine that promotes the differentiation & viability of monocytes & macrophages through the colony-stimulating factor-1 receptor & is a part of a group of cytokines called interleukins. IL34 increases growth or survival of immune cells known as monocytes. IL34 protein obtains its activity by binding the Colony stimulating factor 1 receptor. Interleukin 34 has also a potential part in viral infection, the adaptive immune response & bone marrow cell proliferation. Furthermore, IL34 plays an important role in innate immunity & in inflammatory processes.IL34 Human Recombinant produced in CHO cells is a glycosylated homodimeric polypeptide chain containing 228 amino acids & having a total molecular mass of 26kDa.IL34 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

DETAILS

Format Id: Lyophilized from a sterile (0.2µ) filtered solution containing phosphate buffered saline (PBS).
Amino Acid: NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRLQRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSPKVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCSPEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHH
Purification: Greater than 95.0% as determined by SDS-PAGE.
Alternative Name: Interleukin 34, C16orf77, MGC34647, IL34
Application Note: It is recommended to reconstitute the lyophilized IL34 in sterile water at a concentration of 0.1 mg/ml, which can then be further diluted to other aqueous solutions.
Storage Condition: Lyophilized IL34 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL34 Human should be stored at 4°C between 2-7 days & for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.