Recombinant Rat FGF-10

DESCRIPTION

FGF‐10 is a heparin‐binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF‐10 is most related to KGF/FGF‐7, and is expressed during the development and, preferentially, in adult lungs. It signals through FGFR 2b. Recombinant Rat FGF‐10 is a 20.2 kDa protein consisting of 180 amino acid residues.

DETAILS

Gene Id: 25443
Uniprot: P70492
Activity: Assay #1: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8). Assay #2: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 1-5 ng/ml.
Category: RUO Cytokines
Subcategory: Growth Factors & Cytokines
Research Areas: Angiogenesis/Cardiovascular, Bone, Skeletal, Cartilage, Cancer, FGF Superfamily, Immune System, Inflammation, Neurobiology, Wound Healing, Stem Cells and Differentiation, Organoids
Alternative Names: Fibroblast Growth Factor‐10, FGFA, Keratinocyte Growth Factor‐2
Species of Origin: Rat
Expression System Source: E.coli