E2588Mo
Scientist.com Supplier
Mouse Transcription Factor Hes-1, HES1 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
DETAILS
- Gene Id: 15205
- Uniprot: P35428
- Lead Time: 3 days
- Assay Type: Sandwich
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 0.098ng/ml
- Detection Range: 0.2-60ng/ml
- Detection Method: ELISA
- Species Reactivity: Mouse