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E2588Mo

Mouse Transcription Factor Hes-1, HES1 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).

DETAILS

  • Gene Id: 15205
  • Uniprot: P35428
  • Lead Time: 3 days
  • Assay Type: Sandwich
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.098ng/ml
  • Detection Range: 0.2-60ng/ml
  • Detection Method: ELISA
  • Species Reactivity: Mouse