Skip to Main Content
Welcome to the Scientist.com Marketplace

Go to Main Navigation

E2588Mo

Mouse Transcription Factor Hes-1, HES1 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).

DETAILS

  • GeneID: 15205
  • Species: Mouse
  • Storage: 2-8ºC
  • MASS(Da): 29,749
  • Synonyms: Hairy and enhancer of split 1;HES 1;HES1;Transcription factor HES-1
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: HES1
  • Reactivity: Mouse
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.098ng/ml
  • Target Protein: HES1
  • Detection Range: 0.2-60ng/ml
  • Full Product Name: Transcription Factor Hes-1
  • Standard Solution: 64ng/ml
  • UniProt Accession: P35428