DESCRIPTION

• Mw: 33.3 kDa
• Tag: Myc-DDK
• Accn: NM_001190906
• Type: Human Tagged ORF Clone Lentiviral Particle
• Refseq: NM_001190906.1
• Status: 7 Weeks*
• Symbol: AKR1D1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Category: cDNA Clones
• Locus Id: 6718
• Orf Size: 855 bp
• Synonyms: 3o5bred; CBAS2; SRD5B1
• Refseq Orf: 858 bp
• Uniprot Id: P51857
• Availability: 7 Weeks
• Cytogenetics: 7q33
• Gene Summary: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]
• Sequence Data: ORF Nucleotide Sequence ( show hide ) The ORF insert of this clone is exactly the same as(RC231126).
• Oti Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Oti Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Protein Families: Druggable Genome
• Protein Pathways: Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways, Primary bile acid biosynthesis
• Mammalian Cell Selection: Puromycin