Anti-ATG9A Antibody [SC67-05]

DESCRIPTION

Autophagy, a process that results in the lysosomal-dependent degradation of cytosolic compartments, is carried out by the autophagosome, which is a double-membrane vesicle whose formation is catalyzed by several autophagy-related gene (Atg) proteins. Atg9a (autophagy-related protein 9A), also known as APG9-like 1, is a 839 amino acid, multi-pass membrane protein that localizes to the pre-autophagosomal structure (PAS). Isolation membranes are suggested to originate from the PAS, enwrapping cytoplasmic components to form a double membrane autophagosome, which then fuses with the vacuole. Ubiquitously expressed in human adult tissues, Atg9a cycles between the Golgi and endosomes and, with the autophagosome-specific marker LC3, plays a critical role in starvation-induced autophagosome formation. Three isoforms of Atg9a exist as a result of alternative splicing events.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: Q7Z3C6 Human;SwissProt: Q68FE2 Mouse;SwissProt: Q5FWU3 Rat
Clone Id: SC67-05
Clonality: Recombinant Rabbit monoclonal Antibody
Conjugate: Non-conjugated
Alias Names: APG9 autophagy 9-like 1 antibody APG9 like 1 antibody APG9-like 1 antibody APG9L1 antibody ATG9 antibody ATG9 autophagy related 9 homolog A antibody ATG9 autophagy related 9 homolog A (S. cerevisiae) antibody ATG9A antibody ATG9A_HUMAN antibody Autophagy 9-like 1 protein antibody Autophagy related protein 9A antibody Autophagy-related protein 9A antibody mATG9 antibody MGD3208 antibody OTTHUMP00000206046 antibody OTTHUMP00000206048 antibody OTTHUMP00000206049 antibody OTTHUMP00000206062 antibody
Application: WB,IF-Cell,IHC-P,IP
Epitope Region: Synthetic peptide within Human ATG9A aa 799-839 / 839.
Protein Target: ATG9A
Target Species: Human,Mouse,Rat
Species Reactivity: Human,Mouse,Rat