T80166
α-Conotoxin BuIA
TargetMol
DESCRIPTION
α-Conotoxin BuIA is a paralytic peptide neurotoxin that acts as a competitive antagonist of nicotinic acetylcholine receptors (nAChR), with inhibitory concentration 50 (IC50) values of 0.258 nM for α6/α3β2, 1.54 nM for α6/α3β4, and 5.72 nM for α3β2. It serves to differentiate between nAChRs containing the β2- and β4-subunits and selectively inhibits αxβ2 nAChRs, exhibiting a potency hierarchy of α6>α3>α2>α4 [1].
DETAILS
- Cas: 846539-62-6
- Purity: 98%
- Category: Compound
- Molecular Weight: 1311.57
- Molecular Formula: C54H82N14O16S4
Lead Time: Please Inquire
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