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Recombinant Human Endostatin



Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs, with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.


  • Gene Id: 80781
  • Uniprot: P39060
  • Activity: Measured by its ability to inhibit HUVEC migration.
  • Category: RUO Cytokines
  • Subcategory: Growth Factors & Cytokines
  • Research Areas: Angiogenesis/Cardiovascular, Immune System
  • Alternative Names: COL18A1
  • Species of Origin: Human
  • Expression System Source: E.coli