MST4 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 51765
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: STK26
Other Names: Serine/threonine-protein kinase 26, MST3 and SOK1-related kinase, Mammalian STE20-like protein kinase 4, MST-4, STE20-like kinase MST4, Serine/threonine-protein kinase MASK, STK26 (HGNC:18174)
Availability: 2 weeks
Bio Background: The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Bio References: Sung, V., et al., Cancer Res. 63(12):3356-3363 (2003).Lee, K.K., et al., J. Biol. Chem. 277(14):12351-12358 (2002).Dan, I., et al., J. Biol. Chem. 277(8):5929-5939 (2002).Lin, J.L., et al., Oncogene 20(45):6559-6569 (2001).Qian, Z., et al., J. Biol. Chem. 276(25):22439-22445 (2001).
Other Accession: NP_057626
Primary Accession: Q9P289
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7925a was selected from the C-term region of human MST4 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.