IL-17A, Mouse

DESCRIPTION

Interleukin-17A, (also known as CTLA-8) is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpesvirus Saimiri. cDNA clones encoding IL-17 have been isolated from activated rat, mouse and human T cells. IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers.

DETAILS

Form: Lyophilized
Purity: > 95% as analyzed by SDS-PAGE
Species: Mouse
Product Line: Cytokines
Expression System: CHO
Storage Stability: Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Biological Activity: Measured by its ability to induce IL-1a, IL-4 and IL-6 production by primary mouse splenocytes.
Protein Construction: IL-17A (Ala26-Ala158)\nAccession # Q62386