mouse monoclonal IgG1; C/EBP ε Antibody (C-10) is an IgG1 κ mouse monoclonal C/EBP epsilon antibody (also designated CEBPE antibody, or C/EBP epsilon antibody) that detects the C/EBP epsilon protein of mouse, rat and human origin by WB, IP, IF and ELISA. C/EBP ε Antibody (C-10) is available as both the non-conjugated anti-C/EBP epsilon antibody form, as well as multiple conjugated forms of anti-C/EBP epsilon antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The transcription factor C/EBP α (CCAAT-enhancer binding protein) is a heat-stable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic α helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP α appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP β, C/EBP γ, C/EBP δ and C/EBP e, all of which exhibit similar DNA-binding specificities and affinities to C/EBP α. Furthermore, C/EBP β and C/EBP δ readily form heterodimers both with each other as well as with C/EBP α.