T5S0045
Isofraxidin
TargetMol
DESCRIPTION
1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. 3. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
DETAILS
- Cas: 486-21-5
- Purity: 99.65%
- Smiles: COc1cc2ccc(=O)oc2c(OC)c1O
- Category: Compound
- Molecular Weight: 222.19
- Molecular Formula: C11H10O5
Lead Time: < 1 week
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