mouse monoclonal IgG1; Centriolin Antibody (C-9) is an IgG1 κ mouse monoclonal Centriolin antibody (also designated Centriolin antibody) that detects the Centriolin protein of human origin by WB, IP, IF, IHC(P) and ELISA. Centriolin Antibody (C-9) is available as both the non-conjugated anti-Centriolin antibody form, as well as multiple conjugated forms of anti-Centriolin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Cytokinesis occurs during the late stages of mitosis and describes the process by which the cytoplasm of one cell is divided to create two subsequent daughter cells. Centriolin, also known as CEP110, is a coiled-coil centrosomal protein that is required for centrosome maturation and correct centrosome function. During abscission, the last step in cytokinesis, Centriolin both coordinates and grounds vesicle-fusion and vesicle-exocyst complexes to the midbody of the daughter cells. Acting as an anchor for the protein complexes needed to complete separation of the two cells, Centriolin initiates and controls vesicle-mediated cell cleavage. Through its ability to signal initiation of the last step of vertebrate cytokinesis, Centriolin regulates cell proliferation and contributes to proper entry into the S phase of mitosis.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.