Fluorescent Dye Label: Dil Surface Coating: Carboxyl Amount: 50 mg Description Our single-layer poly (lactic-co-glycolic acid) (PLGA) nanoparticles form nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. Dye molecules and magnetic nanoparticles are encapsulated inside the hydrophobic core. PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry) Features Made with FDA approved biocompatible and biodegradable PLGA polymer. Conjugation-ready for covalent attachment of biomolecules. High degree of monodispersity. Can be pulled down by application of magnetic force. Labeled with a fluorescent dye. (Optional) Incorporation of Methoxy-PEG minimizes non-specific protein adsorption. This increase nanoparticle in-vivo blood half-life. (Optional) Incorporation of Azide-PEG allows conjugation of proteins and small molecules by click chemistry. Applications Dual labeled fluorescence and magnetic nanoparticles for in-vivo tar-geting. Dual fluorescence and MRI imaging for in vitro and in vivo applications. Dual labeled fluorescence and magnetic probes for magnetic cell pull-down and flowcytometry analysis. In vitro and in vivo delivery of proteins and small molecules. Product is supplied as lyophilized powder.